QEEG (quantitative EEG) captures resting-state brain wave patterns — power, coherence, and frequency distributions while a person sits still with eyes open and closed. It is useful for detecting clinical pathology (significant deviations from norm), but has limitations for precision brain age measurement: results fluctuate with mood, sleep, caffeine, and what the person is thinking about; test-retest reliability varies; and interpretation can differ between clinicians reviewing the same data.
Brain age clocks derived from resting-state EEG have been published in the research literature — for example, Al Zoubi et al. (2018) reported MAE of ~6.9 years from eyes-closed resting EEG, and Engemann et al. (2022) reported similar ranges. However, none have achieved the accuracy of task-based approaches (BrainYears™ achieves MAE 4.4 years), and none have moved beyond research into commercial or clinical application.
BrainYears™ controls for these variables by measuring the brain under a standardized cognitive task, producing stable, repeatable functional biomarkers that are independent of daily state fluctuation.
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